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SARMs work similarly to testosterone in that they fill the same androgen receptor. While men tend to have higher levels of testosterone, as well as sex hormones (androsterone and progesterone), there is an imbalance in the ratio of testosterone and androsterone, which causes sexual desire and erectile dysfunction.This imbalance can easily be dealt with, but the male response is not an easy one, and requires a holistic treatment approach in conjunction with medicine."We believe that as a gender, we all fall within a sex-specific, hormonal and neurological spectrum," explains Dr. Stuckey. "And this spectrum is the one that we're most passionate about."Although they are able to perform "normal" tasks like reading, driving, and brushing their teeth, women report lower levels of libido and desire for sex -- and this manifests as lowered mood and fatigue, less interest in men and even depression, anxiety and loneliness and even a loss of appetite.One of the primary reasons this imbalance is common among men with ME/CFS is an increased immune suppression from their illness. Men experience a higher response to an autoimmune response in the body: a combination of the immune system and hormone levels that cause a fight-or-flight response. There are several types of immune suppression -- from a lack of body tissue, to an increase in cytokines and an increase in inflammation as a result of infection.The increase in cytokines can lead to fatigue, difficulty focusing, and even depression. Other factors contributing to this imbalance are increased blood flow between the body and brain, an increase in prolactin, and estrogen."It's as simple as that," explained Dr. Stuckey. "We know the problem is biological, but we still have no effective treatments other than the biological remedies."There are several things that can be done to overcome this imbalance, including improving diet and exercise to get around the immune suppression from the disease. While the treatment is effective in some people, it's not necessarily a cure, as there is a very long path from a medical diagnosis of ME/CFS to treatment.It is very important that men understand the nature of their illness, and seek to find out what medications will best work for them. Many have expressed the desire to find better alternatives to the more toxic medications, such as Soma, Cetuximab, Stavudine, Cyazid and others.As Dr. Stuckey explains, "Men who suffer from ME/CFS are atRelated Article: