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Powerful steroids can allow people to add as much as 30 pounds of muscle to their frames in just a few weeks, moobs on holidayor a new crop of baby breasts -- at least, that's what sports-medicine textbooks would have you believe.But steroids, or any other drugs of abuse, can cause serious and long-term health problems, including cancer, heart disease, and heart attacks, if users abuse them regularly and consume large amounts, even over long periods of time.Overuse of steroids can stunt growth hormone production and lead to muscle wasting as the body tries to conserve energy for normal functioning, according to a review of 20,000 cases of steroid use published in 2012 in the American Journal of Medicine.The review was part of the largest such study ever conducted in the United States, using data from the National Heart, Lung, and Blood Institute and the Centers for Disease Control and Prevention.A more recent review published in 2013 in the journal BMJ looked at over 9,600 cases of suspected steroid abuse -- mostly at University of California campuses from the 1970s through the mid-1990s -- using a questionnaire completed by thousands of people before they returned for a physical.Nearly all of the steroid users -- over 90 percent -- failed drug tests for the drugs they were taking.The most dangerous problem was heart disease, a leading cause of death among people who are not obese, said lead author Dr. Robert Langer, an endocrinologist and professor of medicine and director of the Center for Endocrinology and Metabolism at Tufts Medical Center. It was not clear whether the steroids were causing heart disease or were causing it somehow."We don't know yet what the role is of steroid use on cardiorespiratory fitness or risk of cardiovascular disease for long-term exercise performance, whether they affect weight loss and body composition," Langer said in an email.A 2011 study published in the British Medical Journal found an increased risk of heart disease and cancer among steroid users who took blood thinners.Tests showing effects on fat and bone are common, but it's unclear just how often people abuse steroids in real life.The study authors looked at more than 25,000 cases of lifetime steroid use. Participants were asked if they tested positive for any drugs by the National Health and Nutrition Examination Survey, or if they had ever tried a diet drug.Among those who hadn't abused steroid, the incidence of heart disease was 1.9 percent. They were about as likely to have tested positive for blood thinners as they were to use steroids.Similar articles: